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1

Aberrant Interaction of the Gut Immune System with Environmental Factors in the Development of Food Allergies

Jun Kunisawa, Hiroshi Kiyono

Journal:

Current Allergy and Asthma Reports

Year:

2010

Language:

english

File:

PDF, 381 KB

english, 2010

2

Mode of Bioenergetic Metabolism during B Cell Differentiation in the Intestine Determines the Distinct Requirement for Vitamin B1

Kunisawa, Jun, Sugiura, Yuki, Wake, Taichi, Nagatake, Takahiro, Suzuki, Hidehiko, Nagasawa, Risa, Shikata, Shiori, Honda, Kurara, Hashimoto, Eri, Suzuki, Yuji, Setou, Mitsutoshi, Suematsu, Makoto, Kiy

Journal:

Year:

2015

Language:

english

File:

PDF, 2.15 MB

english, 2015

3

High fat diet exacerbates murine psoriatic dermatitis by increasing the number of IL-17-producing γδ T cells

Nakamizo, Satoshi, Honda, Tetsuya, Adachi, Akimasa, Nagatake, Takahiro, Kunisawa, Jun, Kitoh, Akihiko, Otsuka, Atsushi, Dainichi, Teruki, Nomura, Takashi, Ginhoux, Florent, Ikuta, Koichi, Egawa, Gyohe

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.50 MB

english, 2017

4

Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues

Sasaki, Ayana, Nagatake, Takahiro, Egami, Riku, Gu, Guoqiang, Takigawa, Ichigaku, Ikeda, Wataru, Nakatani, Tomoya, Kunisawa, Jun, Fujita, Yasuyuki

Journal:

Year:

2018

Language:

english

File:

PDF, 3.89 MB

english, 2018

5

Development of antigen delivery system for mucosal vaccine; ワクチンデリバリーを基盤とした粘膜ワクチン開発;

Suzuki, Hidehiko, Kunisawa, Jun

Journal:

Drug Delivery System

Year:

2018

File:

PDF, 1.28 MB

2018

6

Analysis of oral microbiota in Japanese oral cancer patients using 16S rRNA sequencing

Takahashi, Yasuharu, Park, Jonguk, Hosomi, Koji, Yamada, Tomonori, Kobayashi, Ayaka, Yamaguchi, Yuji, Iketani, Susumu, Kunisawa, Jun, Mizuguchi, Kenji, Maeda, Nobuko, Ohshima, Tomoko

Journal:

Journal of Oral Biosciences

Year:

2019

Language:

english

File:

PDF, 1.60 MB

english, 2019

7

Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway

Tsuyoshi Nakanishi, Akira Hayashi, Jun Kunisawa, Yasuo Tsutsumi, Keiichi Tanaka, Yumi Yashiro-Ohtani, Mahito Nakanishi, Hiromi Fujiwara, Toshiyuki Hamaoka, Tadanori Mayumi

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 145 KB

english, 2000

8

Lack of antigen-specific immune responses in anti-IL-7 receptor α chain antibody-treated Peyer's patch-null mice following intestinal immunization with microencapsulated antigen

Jun Kunisawa, Ichiro Takahashi, Akiko Okudaira, Takachika Hiroi, Kazufumi Katayama, Teruko Ariyama, Yasuo Tsutsumi, Shinsaku Nakagawa, Hiroshi Kiyono, Tadanori Mayumi

Journal:

European Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 228 KB

english, 2002

9

All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway

Nilabh Shastri, Sylvain Cardinaud, Susan R. Schwab, Thomas Serwold, Jun Kunisawa

Journal:

Immunological Reviews

Year:

2005

Language:

english

File:

PDF, 784 KB

english, 2005

10

Intraepithelial lymphocytes: their shared and divergent immunological behaviors in the small and large intestine

Jun Kunisawa, Ichiro Takahashi, Hiroshi Kiyono

Journal:

Immunological Reviews

Year:

2007

Language:

english

File:

PDF, 732 KB

english, 2007

11

Protection by Intranasal Immunization of a nef-Deleted, Nonpathogenic SHIV against Intravaginal Challenge with a Heterologous Pathogenic SHIV

Yoshimi Enose, Masahiro Ui, Ariko Miyake, Hajime Suzuki, Hiromi Uesaka, Takeo Kuwata, Jun Kunisawa, Hiroshi Kiyono, Hidemi Takahashi, Tomoyuki Miura, Masanori Hayami

Journal:

Year:

2002

Language:

english

File:

PDF, 173 KB

english, 2002

12

Gut-associated lymphoid tissues for the development of oral vaccines

Jun Kunisawa, Yosuke Kurashima, Hiroshi Kiyono

Journal:

Advanced Drug Delivery Reviews

Year:

2012

Language:

english

File:

PDF, 850 KB

english, 2012

13

Erratum to “Oral feeding of Bifidobacterium bifidum (BGN4) prevents CD4+ CD45RBhigh T cell-mediated inflammatory bowel disease by inhibition of disordered T cell activation” [Clin. Immunol. 123 (2007) 30–39]

Namju Kim, Jun Kunisawa, Mi-Na Kweon, Geun Eog Ji, Hiroshi Kiyono

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 123 KB

english, 2007

14

Oral feeding of Bifidobacterium bifidum (BGN4) prevents CD4+ CD45RBhigh T cell-mediated inflammatory bowel disease by inhibition of disordered T cell activation

Namju Kim, Jun Kunisawa, Mi-Na Kweon, Geun Eog Ji, Hiroshi Kiyono

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 2.66 MB

english, 2007

15

OR.82. Regulation of Sphingosine 1-phosphate-mediated Trafficking of Pathogenic T and Mast Cells for the Control of Food Allergy

Jun Kunisawa, Yosuke Kurashima, Morio Higuchi, Masashi Gohda, Izumi Ishikawa, Naoko Takayama, Hiroshi Kiyono

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 45 KB

english, 2008

16

Fusogenic liposome delivers encapsulated nanoparticles for cytosolic controlled gene release

Jun Kunisawa, Takashi Masuda, Kazufumi Katayama, Tomoaki Yoshikawa, Yasuo Tsutsumi, Mitsuru Akashi, Tadanori Mayumi, Shinsaku Nakagawa

Journal:

Journal of Controlled Release

Year:

2005

Language:

english

File:

PDF, 622 KB

english, 2005

17

Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins

Tsuyoshi Nakanishi, Jun Kunisawa, Akira Hayashi, Yasuo Tsutsumi, Kazuyoshi Kubo, Shinsaku Nakagawa, Mahito Nakanishi, Keiichi Tanaka, Tadanori Mayumi

Journal:

Journal of Controlled Release

Year:

1999

Language:

english

File:

PDF, 145 KB

english, 1999

18

Pharmacotherapy by intracellular delivery of drugs using fusogenic liposomes: application to vaccine development

Jun Kunisawa, Shinsaku Nakagawa, Tadanori Mayumi

Journal:

Advanced Drug Delivery Reviews

Year:

2001

Language:

english

File:

PDF, 569 KB

english, 2001

19

Positively Charged Liposome Functions as an Efficient Immunoadjuvant in Inducing Immune Responses to Soluble Proteins

Tsuyoshi Nakanishi, Jun Kunisawa, Akira Hayashi, Yasuo Tsutsumi, Kazuyoshi Kubo, Shinkasu Nakagawa, Hiromi Fujiwara, Toshiyuki Hamaoka, Tadanori Mayumi

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 110 KB

english, 1997

20

A Novel Vaccine Delivery System Using Immunopotentiating Fusogenic Liposomes

Akira Hayashi, Tsuyoshi Nakanishi, Jun Kunisawa, Masuo Kondoh, Susumu Imazu, Yasuo Tsutsumi, Keiichi Tanaka, Hiromi Fujiwara, Toshiyuki Hamaoka, Tadanori Mayumi

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 79 KB

english, 1999

21

Peaceful Mutualism in the Gut: Revealing Key Commensal Bacteria for the Creation and Maintenance of Immunological Homeostasis

Jun Kunisawa, Hiroshi Kiyono

Journal:

Cell Host & Microbe

Year:

2011

Language:

english

File:

PDF, 252 KB

english, 2011

22

Biological role of Ep-CAM in the physical interaction between epithelial cells and lymphocytes in intestinal epithelium

Tomonori Nochi, Yoshikazu Yuki, Kazutaka Terahara, Ayako Hino, Jun Kunisawa, Mi-Na Kweon, Takahiro Yamaguchi, Hiroshi Kiyono

Journal:

Clinical Immunology

Year:

2004

Language:

english

File:

PDF, 1.17 MB

english, 2004

23

Hsp90α Chaperones Large C-Terminally Extended Proteolytic Intermediates in the MHC Class I Antigen Processing Pathway

Jun Kunisawa, Nilabh Shastri

Journal:

Year:

2006

Language:

english

File:

PDF, 660 KB

english, 2006

24

Gut lymphocyte migration: we are halfway ‘home’

Jerry R. McGhee, Jun Kunisawa, Hiroshi Kiyono

Journal:

Trends in Immunology

Year:

2007

Language:

english

File:

PDF, 621 KB

english, 2007

25

Immunological commonalities and distinctions between airway and digestive immunity

Jun Kunisawa, Tomonori Nochi, Hiroshi Kiyono

Journal:

Trends in Immunology

Year:

2008

Language:

english

File:

PDF, 885 KB

english, 2008

26

Erratum: Immunological commonalities and distinctions between airway and digestive immunity [Trends Immunol. 29 (2008), 505-513]

Jun Kunisawa, Tomonori Nochi, Hiroshi Kiyono

Journal:

Trends in Immunology

Year:

2009

Language:

english

File:

PDF, 322 KB

english, 2009

27

The Group II Chaperonin TRiC Protects Proteolytic Intermediates from Degradation in the MHC Class I Antigen Processing Pathway

Jun Kunisawa, Nilabh Shastri

Journal:

Year:

2003

Language:

english

File:

PDF, 526 KB

english, 2003

28

Characterization of mucoadhesive microspheres for the induction of mucosal and systemic immune responses

Jun Kunisawa, Akiko Okudaira, Yasuo Tsutusmi, Ichiro Takahashi, Tsuyoshi Nakanishi, Hiroshi Kiyono, Tadanori Mayumi

Journal:

Year:

2000

Language:

english

File:

PDF, 250 KB

english, 2000

29

Microbe-dependent CD11b+ IgA+ plasma cells mediate robust early-phase intestinal IgA responses in mice

Kunisawa, Jun, Gohda, Masashi, Hashimoto, Eri, Ishikawa, Izumi, Higuchi, Morio, Suzuki, Yuji, Goto, Yoshiyuki, Panea, Casandra, Ivanov, Ivaylo I., Sumiya, Risa, Aayam, Lamichhane, Wake, Taichi, Tajiri

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

30

Acid-Degradable Particles for Protein-Based Vaccines: Enhanced Survival Rate for Tumor-Challenged Mice Using Ovalbumin Model

Standley, Stephany M., Kwon, Young Jik, Murthy, Niren, Kunisawa, Jun, Shastri, Nilabh, Guillaudeu, Steven J., Lau, Lana, Fréchet, Jean M. J.

Journal:

Bioconjugate Chemistry

Year:

2004

Language:

english

File:

PDF, 163 KB

english, 2004

31

Immune regulation and monitoring at the epithelial surface of the intestine

Kunisawa, Jun, Kiyono, Hiroshi

Journal:

Drug Discovery Today

Year:

2013

Language:

english

File:

PDF, 574 KB

english, 2013

32

[IEEE 2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS) - San Francisco, CA, USA (2014.01.26-2014.01.30)] 2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS) - Microfluidic electrochemiluminescence (ECL) integrated flow cell for portable fluorescence detection

Tsuwaki, Miho, Mizuno, Jun, Kasahara, Takashi, Edura, Tomohiko, Kunisawa, Eri, Ishimatsu, Ryoichi, Matsunami, Shigeyuki, Imato, Toshihiko, Adachi, Chihaya, Shoji, Shuichi

Year:

2014

Language:

english

File:

PDF, 2.11 MB

english, 2014

33

Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors

Kurashima, Yosuke, Amiya, Takeaki, Nochi, Tomonori, Fujisawa, Kumiko, Haraguchi, Takeshi, Iba, Hideo, Tsutsui, Hiroko, Sato, Shintaro, Nakajima, Sachiko, Iijima, Hideki, Kubo, Masato, Kunisawa, Jun, K

Journal:

Nature Communications

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

34

Role of Lactobacillus pentosus Strain b240 and the Toll-Like Receptor 2 Axis in Peyer's Patch Dendritic Cell-Mediated Immunoglobulin A Enhancement

Kotani, Yoshifumi, Kunisawa, Jun, Suzuki, Yuji, Sato, Ikutaro, Saito, Takao, Toba, Masamichi, Kohda, Noriyuki, Kiyono, Hiroshi, Bayry, Jagadeesh

Journal:

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

35

Nutritional components regulate the gut immune system and its association with intestinal immune disease development

Lamichhane, Aayam, Kiyono, Hiroshi, Kunisawa, Jun

Journal:

Journal of Gastroenterology and Hepatology

Year:

2013

Language:

english

File:

PDF, 1.09 MB

english, 2013

36

Suppression of Allergic Diarrhea in Murine Ovalbumin-Induced Allergic Diarrhea Model by PG102, a Water-Soluble Extract Prepared from Actinidia arguta

Kim, Donghyun, Kim, Seon Hee, Park, Eun-Jin, Kim, Jiyoung, Cho, Sang-Heon, Kagawa, Junko, Arai, Naoko, Jun, Kunisawa, Kiyono, Hiroshi, Kim, Sunyoung

Journal:

International Archives of Allergy and Immunology

Year:

2009

Language:

english

File:

PDF, 331 KB

english, 2009

37

Mucosa-Associated Lymphoid Tissues in the Aerodigestive Tract: Their Shared and Divergent Traits and Their Importance to the Orchestration of the Mucosal Immune System

Kunisawa, Jun, Fukuyama, Satoshi, Kiyono, Hiroshi

Journal:

Current Molecular Medicine

Year:

2005

Language:

english

File:

PDF, 355 KB

english, 2005

38

Vitamin-Mediated Regulation of Intestinal Immunity

Kunisawa, Jun, Kiyono, Hiroshi

Journal:

Frontiers in Immunology

Year:

2013

Language:

english

File:

PDF, 835 KB

english, 2013

39

Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome

Takemura, Naoki, Kawasaki, Takumi, Kunisawa, Jun, Sato, Shintaro, Lamichhane, Aayam, Kobiyama, Kouji, Aoshi, Taiki, Ito, Junichi, Mizuguchi, Kenji, Karuppuchamy, Thangaraj, Matsunaga, Kouta, Miyatake,

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 2.94 MB

english, 2014

40

Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis

Takashi Obata, Yoshiyuki Goto, Jun Kunisawa, Shintaro Sato, Mitsuo Sakamoto, Hiromi Setoyama, Takahiro Matsuki, Kazuhiko Nonaka, Naoko Shibata, Masashi Gohda, Yuki Kagiyama, Tomonori Nochi, Yoshikazu

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.49 MB

english, 2010

41

[Methods in Microbiology] Immunology of Infection Volume 37 || Analysis of Intestinal T Cell Populations and Cytokine Productions

Year:

2010

Language:

english

File:

PDF, 1.21 MB

english, 2010

42

Salt-inducible kinase 3 deficiency exacerbates lipopolysaccharide-induced endotoxin shock accompanied by increased levels of pro-inflammatory molecules in mice

Sanosaka, Masato, Fujimoto, Minoru, Ohkawara, Tomoharu, Nagatake, Takahiro, Itoh, Yumi, Kagawa, Mai, Kumagai, Ayako, Fuchino, Hiroyuki, Kunisawa, Jun, Naka, Tetsuji, Takemori, Hiroshi

Journal:

Year:

2015

Language:

english

File:

PDF, 535 KB

english, 2015

43

Metabolic changes during B cell differentiation for the production of intestinal IgA antibody

Journal:

Cellular and Molecular Life Sciences

Year:

2017

Language:

english

File:

PDF, 756 KB

english, 2017

44

Uniqueness of the Mucosal Immune System for the Development of Prospective Mucosal Vaccine

KUNISAWA, Jun, GOHDA, Masashi, KIYONO, Hiroshi

Journal:

YAKUGAKU ZASSHI

Year:

2007

File:

PDF, 829 KB

2007

45

The Development of Mucosal Vaccine Using Bacterial Function for Targeting Mucosal Tissues

Suzuki, Hidehiko, Kondoh, Masuo, Yagi, Kiyohito, Kiyono, Hiroshi, Kunisawa, Jun

Journal:

YAKUGAKU ZASSHI

Year:

2014

File:

PDF, 549 KB

2014

46

The Cutting Edge of Epithelium-targeted Drug Development

Kondoh, Masuo, Kunisawa, Jun

Journal:

YAKUGAKU ZASSHI

Year:

2014

File:

PDF, 135 KB

2014

47

Effect of a Flowchart for Basic Motor Skills Practice on Recovery of Cases of Cerebral Hemorrhage Confined to the Putamen

MATSUMOTO, Takahiko, KUNISAWA, Yousuke, TAKEI, Keiichi, YABUSAKI, Jun, KOBAYASHI, Saki, KOBAYASHI, Daiyuu, KUNISAWA, Yoshie, TAKAKURA, Yasuyuki, MAEKAWA, Muneyuki, SHIMOMATSU, Tomoya, YAMAMOTO, Mitsur

Journal:

Rigakuryoho Kagaku

Year:

2012

File:

PDF, 517 KB

2012

48

Complexation hydrogels as potential carriers in oral vaccine delivery systems

Yoshida, Mia, Kamei, Noriyasu, Muto, Keiya, Kunisawa, Jun, Takayama, Kozo, Peppas, Nicholas A., Takeda-Morishita, Mariko

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2017

Language:

english

File:

PDF, 510 KB

english, 2017

49

Immunological Function of Sphingosine 1-Phosphate in the Intestine

Kunisawa, Jun, Kiyono, Hiroshi

Journal:

Year:

2012

Language:

english

File:

PDF, 1.27 MB

english, 2012

50

IL-10-producing CD4+ T cells negatively regulate fucosylation of epithelial cells in the gut

Goto, Yoshiyuki, Lamichhane, Aayam, Kamioka, Mariko, Sato, Shintaro, Honda, Kenya, Kunisawa, Jun, Kiyono, Hiroshi

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 2.18 MB

english, 2015